​Sane Science Nutritions

The average weight loss on the VLCD program is in the range of 3 to 5 pounds per week.


THE PROTEIN LEVERAGE HYPOTHESIS
‘Protein leverage hypothesis’, a theory that may hold clues to why we are collectively putting on weight.

  • The Protein Leverage Hypothesis (PLH) suggests that protein plays a key mediating role mediating in the development of obesity, through its interaction with fat and carbohydrates is not well understood.
  • PLH predicts that humans prioritize protein when regulating food intake.
  • In doing so, humans will consequently over-consume fats and carbohydrates If we consume diet high in protein, but with calorie restriction, we will use consume less fat and carbohydrate
  • All three macronutrients, carbohydrates, fat and protein, exert some degree of influence over total energy intake,  but protein is the most satiating and tightly regulated macronutrient
  • Small changes in the proportion of protein in the diet modify total energy intake
  • Regulation of protein intake dominates non-protein intake
  • Calories derived from protein will remain relatively constant compared to calories from fat and carbohydrates


Medical Treatment
Bariatric Surgery

Herbal and alternative therapy
Many herbs are found to be effective in losing weight and improve metabolism. Various scientific studies endorse the efficacy of these herbs. Some of these are Garcinia Cambogia, Colues Forskilin, GREEN COFFEE, Green tea, Commiphora mukul, Dry Ginger and garlic(Allium Sativum Bulbs​

There is a general view that almost no one succeeds in long-term maintenance of weight loss. Wrong it is only your strong will power, disciplined lifestyle and strictly followed workout plan that can help to loss weight and maintain this lost weight.
Engage in high levels of physical activity (≈1 h/d)
Eat a low-calorie, low-fat diet
Eat breakfast regularly
Self-monitoring weight

There are few theories that has medically proven and documented. 

WHO (World Health Organization) recommends VLED (Very low Energy Diet) under strict medical supervision.

  • Very low energy diets (VLED), alternatively referred to as very low calorie diets (VLCD), consist of proprietary formula foods which provide the sole source of daily energy intake.
  • They usually supply a minimum of 50 g of carbohydrate and 50 g of protein, but must provide all essential nutrient requirements daily, and may contain between 450 and 800 kcals overall.
  • The VLED is intended to induce ketosis, which has an appetite suppressant effect, during which lipolysis converts fat stores into transformable energy

As per Codex Standard (CODEX STAN 203-1995) VLED formula must be as below

  • Protein · Not less than 50 g protein with a high quality, high biological value and PDCAAS score 1 shall be present in the recommended daily intake of energy. Essential amino acids may be added to improve protein quality only in amounts necessary for this purpose. Only L-forms of amino acids shall be used, except that DL-methionine may be used.
  • Fats: Very low energy diets shall provide not less than 3 g of linoleic acid and less than 0.5 g alpha-linolenic acid in the recommended daily intake with the linoleic acid/alpha-linolenic acid ratio between 5 and 15
  • Carbohydrates: Very low energy diets shall provide not less than 50 g of available carbohydrates in the recommended daily intake of energy.
  • Vitamins and Minerals: Very low energy diets shall provide 100% of the recommended daily intakes for vitamins and minerals
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